If you get canker sores
Some people with recurrent canker sores try SLS-free toothpaste. The evidence is limited, so talk to your dentist if sores keep coming back.
In Klyyr's 2026 audit, SLS was listed on products from Aquafresh, Arm & Hammer, CariFree (Gel 1100), Close-Up, Colgate, Crest, Marvis, Parodontax, Apagard (Premio), and Sensodyne (Repair & Protect, US). That is 14 of 50 products.
Some do. 6 of the 23 whitening pastes Klyyr recorded list SLS: Crest 3D White Brilliance, Crest Pro-Health Advanced, Colgate Total SF Whitening, Arm & Hammer Advance White Extreme Whitening, Aquafresh Extreme Clean Whitening Action, and Close-Up Freshening Gel Red. The other 17 do not.
SLS is a permitted detergent that makes toothpaste foam. The ADA lists it among ingredients reported as contact irritants. A systematic review of four crossover trials suggested possible benefit from SLS-free toothpaste for people with recurrent canker sores and called for stronger research.
No. One+ uses sodium cocoyl glutamate as its surfactant and foams less than a typical SLS toothpaste.