Klyyr One+ natural mint hydroxyapatite toothpaste tube floating with mint leaves and mineral crystals

NEW 10% HAp

new fluoride-free toothpaste Best overall 2026 · Exact-Net →

20 reviews

One+

fluoride-free, natural, hydroxyapatite toothpaste

Made with the mineral teeth are made of
Supports enamel remineralization
10% nano + micro hydroxyapatite
No SLS · no artificial dyes · fluoride-free

How you'd like it

One-time $12.95 · 120g · 14¢ per brush Ships once · no commitment

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Subscribe $9.71 ~~Regular price $12.95~~ · 120g · 11¢ per brush Delivered every month · skip, pause or cancel

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Tested every lot

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Full ingredient list — 16

Water, Sorbitol, Glycerin, Potassium Sorbate, Hydroxyapatite (nano & micro), Xylitol, Sodium Cocoyl Glutamate, Cellulose Gum, Xanthan Gum, Zinc Citrate, Aloe Vera, Mentha Piperita (Peppermint) Oil, Mentha Viridis (Spearmint) Leaf Oil, Menthol, Sodium Benzoate, Stevia Rebaudiana Leaf/Stem Extract.

How to use

Use a pea-sized amount on a soft-bristle brush for two minutes, morning and night. Spit — don't rinse — so a light mineral film stays on the teeth. For children under 3 use a rice-grain amount; ages 3–6 use a pea-sized amount with supervision.

Product facts

Paste. 120 g · 4.23 oz per tube, approximately 90 brushings. pH 7.4 ± 0.2. Abrasivity RDA 62 — low. Fluoride 0 ppm. SLS-free, no artificial dyes. Developed and fulfilled in Utah, USA.

Shipping & returns

In-stock orders are processed in 1–2 business days, excluding weekends and holidays. Carrier transit time is additional. Eligible U.S. orders of $20 or more after discounts qualify for free standard shipping. Contact us within 60 days for help under our satisfaction guarantee; see the refund policy for terms.

How the subscription works

One tube a month at the subscriber price. Skip a month, push the date back, swap pack size, or cancel from your account. No skip fees and no phone call.

89%

of adults using a 10% hydroxyapatite toothpaste had no increase in the study’s decay index over 18 months. The formula was non-inferior to 1450 ppm fluoride for that endpoint. The study tested a different formula, not Klyyr One+.

View the study →

What's inside

Clean, listed.

Sixteen ingredients. Each one chosen for a reason — nothing hiding behind "natural flavors."

Seen up close

Specimen plates

Purified Water used in Klyyr One+ toothpaste — Water Purified

Birch-derived Xylitol used in Klyyr One+ toothpaste — Xylitol Birch-derived

Leaf Extract Aloe Vera used in Klyyr One+ toothpaste — Aloe Vera Leaf Extract

Spearmint Mentha Viridis used in Klyyr One+ toothpaste — Mentha Viridis Spearmint

Purified

The formula base.

10% active

A clearly disclosed 10% nano and micro blend selected using published ingredient-level research.

Plant-derived

A non-fermentable sweetener used for flavor and oral-care support.

Leaf Extract

Contributes to the paste's smooth mouthfeel.

Essential oil

Rounds out the peppermint with a softer, sweeter mint character.

Plant-derived

Helps maintain moisture and contributes to a smooth, even paste texture.

Vegetable-derived

A humectant that helps the paste stay smooth and keeps your mouth feeling hydrated after brushing.

Food-grade

Helps preserve the formula during its shelf life.

Amino acid-derived

A sulfate-free surfactant that helps the paste disperse with light foam.

Plant fiber

Stabilizes the paste so it holds together — no separation, no grit.

Fermented

Works with cellulose gum to give the paste its body and spreadability.

Mineral

Supports fresh breath by helping neutralize odor-causing compounds.

Essential oil

Provides the formula's peppermint note.

Cooling flavor

Adds a light cooling finish.

Food-grade

Works with potassium sorbate to keep the formula shelf-stable.

Plant-derived

Balances the mint flavor with light sweetness.

Particle science

Two mineral sizes. Two interaction scales.

Klyyr hydroxyapatite toothpaste — Extreme close-up of a bright, healthy smile with glossy lips

Nano and micro hydroxyapatite are the same enamel-like mineral at two particle-size ranges. Published ingredient research examines how smaller particles interact with microscopic defects and dentinal tubules while larger particles remain closer to the tooth surface. One+ includes both at a combined 10% concentration.

Nano

20–100 nm

Finer-scale contact

Micro

5–10 microns

Surface-scale contact

Nano-hydroxyapatite

The finer-scale crystal.

Ultra-fine crystals are studied for their interaction with microscopic surface defects and exposed dentinal tubules.

Scale: About 20–100 nanometers. Shown here as a single elongated hexagonal prism, much larger than life.
Shape: Cylinder-like, with six flat sides — the hexagonal crystal system hydroxyapatite forms naturally.
Role: Smaller particles are studied for their interaction with microscopic surface defects and exposed dentinal tubules.

Drag · to rotate

Scroll · to explore

Single hexagonal crystal CylinderGeometry · 6 radial segments

Drag · to rotate

Scroll · to explore

Fused crystallite aggregate InstancedMesh · 380 hexagonal rods

Micro-hydroxyapatite

The surface-scale cluster.

Larger mineral clusters remain closer to the tooth surface, where ingredient studies examine their contribution to a mineral layer.

Scale: Typically 5–10 microns — fifty to five hundred times larger than an individual nano crystal.
Shape: Not one giant rod, but hundreds of tiny crystallites fused into a porous, mostly spherical cluster.
Role: Larger particles remain closer to the tooth surface in published ingredient research.

01 The mineral

10% Hydroxyapatite

Nano + micro hydroxyapatite at a clearly disclosed combined concentration.

02 Formula specification

pH 7.4

Measured formula target: pH 7.4 ± 0.2.

03 By design

Fluoride · 0 ppm

A fluoride-free formula by design.

Klyyr One+ hydroxyapatite toothpaste tube

04 Light foam

SLS-free

Uses sodium cocoyl glutamate instead of sodium lauryl sulfate.

05 Check locally

Clean tube

Rinse and separate the HDPE cap; recycle each component where accepted locally.

06 Nothing extra

16 ingredients

Each one is doing work. None of them are there to look good on a label.

Form

Paste

Net wt.

120 g · 4.23 oz

Brushings

~ 90

7.4 ± 0.2

Abrasivity (RDA)

62 · low

Country

Developed and fulfilled in Utah, USA

Klyyr hydroxyapatite toothpaste — A happy couple walking through a colorful meadow

FIRST BRUSH

Mint-forward, with light foam.

Expect a smooth paste, a peppermint-and-spearmint profile, and less foam than an SLS toothpaste.

sensory
TWICE DAILY

Consistency creates contact time.

Brush gently for two minutes, morning and night. Spit after brushing rather than intentionally swallowing.

routine
WEEKS 2–4

What ingredient studies measure.

Studies of other hydroxyapatite toothpaste formulas have measured changes in sensitivity over this range. Results vary, and those studies are not clinical tests of One+.

evidence
~90 BRUSHINGS

The useful tube fact.

Each tube contains 120 g / 4.23 oz and provides approximately 90 brushings. Actual use varies by person and amount used.

120 g

How it works

How hydroxyapatite meets enamel.

A magnified cross-section. Nano crystals settle into microscopic defects & micro clusters stay on the surface as a mineral protective coat.

Nano · 20–100 nm

Micro · 5–10 μm

01Nano

02Micro

03Combined

Tooth enamel, magnified.

Sugar, acid and daily wear leave the outer enamel pitted with microscopic defects. Press Apply to see hydroxyapatite in action.

Illustration of particle-size concepts from published hydroxyapatite ingredient research. Not a clinical simulation of Klyyr One+, and not a promise of personal results. One+ uses nano + micro hydroxyapatite at a combined 10% concentration.

Formula The difference	Fluoride toothpaste Typical	10% hydroxyapatite Klyyr ONE+
Hydroxyapatite	None	10% nano + micro
Fluoride	1000–1450 ppm	0 ppm
SLS	Often used	None
Artificial dyes	Often used	None
Ingredient list	30+ ingredients	only 16
Particle sizes	Rarely disclosed	Nano + micro

Typical values describe common conventional fluoride toothpastes. Individual formulas vary. One+ facts are from the product label.

View steps

Use a pea-sized amount

Apply ONE+ to a soft-bristle toothbrush. A little goes a long way.
Brush for two minutes

Brush gently, morning and night, reaching every surface of every tooth.
Spit. Don't rinse.

Spit after brushing. Follow the product directions and any advice from your dentist.

For children under 3, use a rice-grain amount; for ages 3–6, use a pea-sized amount. Supervise brushing and encourage children to spit rather than intentionally swallow.

01 How do I use ONE+?

Brush twice daily with a pea-sized amount for two minutes. Spit without rinsing so a light film remains on the teeth. Use a soft-bristle brush and brush gently; consistency matters more than pressure.

02 How does hydroxyapatite compare with fluoride?

Hydroxyapatite is a fluoride-free alternative with growing clinical evidence. In one 18-month adult study, a 10% HAp toothpaste was non-inferior to 1450 ppm fluoride for the study's primary caries endpoint. That study tested a different formula, so it is ingredient-level evidence—not a Klyyr clinical result. Read the hydroxyapatite vs fluoride comparison.

03 Why use both nano- and micro-hydroxyapatite?

Nano and micro refer to particle-size ranges. Published ingredient research examines how smaller particles interact with microscopic surface defects and dentinal tubules, while larger particles remain closer to the tooth surface. One+ includes both at a combined 10% concentration. Read nano vs micro hydroxyapatite toothpaste.

04 Was Klyyr named best overall 10% nano-hydroxyapatite toothpaste?

Yes. In Exact-Net's 2026 ranking, Dr. Rossouw named Klyyr Best Overall, ahead of Genvyne, Davids, and Mouthology. That is his editorial pick, not a clinical contest. Read the Best Overall recap.

05 Can children use it?

For children under 3, use a rice-grain amount; for ages 3–6, use a pea-sized amount. A caregiver should supervise brushing and encourage children to spit rather than intentionally swallow. Ask your child's dentist about individual needs, especially when switching from a fluoride toothpaste. See hydroxyapatite toothpaste for kids.

06 Does it help with sensitive teeth?

Hydroxyapatite toothpastes have been studied for dentin sensitivity, including their interaction with exposed tubules. Those studies evaluated other formulas, so they do not guarantee a result from One+. Talk with your dentist if sensitivity is severe, new, or persistent. Read hydroxyapatite toothpaste for sensitive teeth.

07 Is ONE+ fluoride-free and SLS-free?

Yes. One+ contains 0 ppm fluoride and uses sodium cocoyl glutamate instead of sodium lauryl sulfate (SLS) for a lower-foam brush. All 16 ingredients are listed above. Read SLS-free hydroxyapatite toothpaste.

08 How long does one tube last?

Each 120 g tube provides approximately 90 brushings. Actual use varies by person and amount used.

09 How does the subscription work?

Choose an available delivery schedule and the current selling-plan savings will be shown before checkout. Skip, pause, or cancel from your account. Shipping cost and eligibility are confirmed at checkout.

Read the full FAQ →

08 — Independent research

Ask someone who isn't us.

Send this to ChatGPT and read what it finds. Change the question if ours is the wrong one.

5 stars: 20 (100%)
4 stars: 0 (0%)
3 stars: 0 (0%)
2 stars: 0 (0%)
1 star: 0 (0%)

You feel a feeling of freshness and immediate cleaning, It's better than I had imagined, deep cleaning, pleasant flavor.

Fresh, not overpowering

The mint is just right for me. fresh enough to feel clean, but not so strong that it lingers forever. I also appreciate how smooth the paste feels.

Feels thoughtfully made

Everything from the flavor to the texture feels well considered. It’s simple, pleasant to use, and gives me that polished feeling after brushing.

my new everyday toothpaste

I wanted a hydroxyapatite toothpaste that still felt like a normal toothpaste, and this is exactly that. It foams nicely, tastes good, and has become an easy part of my routine.

I actually look forward to brushing

The texture and flavor make this surprisingly enjoyable to use. My mouth feels fresh afterward, and there’s no chalky aftertaste.

Pleasantly surprised

I wasn’t sure what to expect, but I liked it from the first brush. The flavor is subtle, the consistency is smooth, and it leaves a genuinely clean feeling.

Clean without the harshness

This leaves my teeth feeling really clean but doesn’t have the sharp, medicinal taste some toothpastes do. It’s fresh, gentle, and easy to use every day.

gentle and refreshing

I’ve found this much more comfortable than toothpastes with a strong burn. It still feels refreshing and cleans well, just in a gentler way.

an easy switch

I’ve been using One+ for a few weeks and the transition was effortless. The texture feels familiar, the flavor is clean, and my mouth feels fresh without that overly intense burn.

Already part of my routine

After a couple of weeks, I don’t really think about the switch anymore—I just reach for it. It feels clean, comfortable, and consistent every time.

No fuss, no weird flavor, and it leaves my teeth feeling smooth and clean. It fits easily into my morning and evening routine.

The paste has a smooth consistency and doesn’t feel gritty. The mint flavor is light and pleasant, which makes it easy to brush for the full two minutes.

Really happy with it

The flavor is pleasant, the texture is smooth, and my teeth feel polished after brushing. It’s been a simple, positive change to my daily routine.

Fresh mouth, no burn

I really like that this gives me a fresh-mouth feeling without being aggressively minty. It rinses clean and doesn’t leave a strong aftertaste.

a clean feeling that lasts

My teeth feel smooth after I use this, and the fresh feeling holds up well through the morning. The flavor is understated and very easy to like.

Definitely worth trying

I was curious about hydroxyapatite and this made it an easy place to start. It brushes like a quality regular toothpaste and has a pleasant, mild flavor.

A simple upgrade

I switched because I wanted a better everyday option without changing my whole routine. One+ feels familiar in the best way and has a clean, balanced taste.

This hits the sweet spot between fresh and gentle. It foams enough, rinses easily, and doesn’t leave my mouth feeling dry afterward.

So far, so good

I’ve only been using it for a little while, but I’m impressed so far. It tastes good, feels gentle, and my teeth feel nice and clean after brushing.

Exactly what I wanted

I was looking for a straightforward toothpaste with hydroxyapatite and a flavor I could actually enjoy every day. This checks both boxes.

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One+

Clean, listed.

Two mineral sizes. Two interaction scales.

The finer-scale crystal.

The surface-scale cluster.

Six things worth pointing at.

A ritual worth repeating .

How hydroxyapatite meets enamel.

Klyyr, versus typical .

Two minutes. Twice a day.

Use a pea-sized amount

Brush for two minutes

Spit. Don't rinse.

Ask someone who isn't us.