One+ hydroxyapatite toothpaste
NEW 10% HAp
NEW

One+

★★★★★
4.86 2,418 verified 120 g · 90 brushings
$12.95

Ten percent nano- and micro-hydroxyapatite — the same mineral your enamel is made of. Fills microscopic erosions, strengthens teeth, and reduces sensitivity. No fluoride trade-off.

View ingredients

Water, Sorbitol, Glycerin, Potassium Sorbate, Hydroxyapatite (nano & micro), Xylitol, Sodium Cocoyl Glutamate, Cellulose Gum, Xanthan Gum, Zinc Citrate, Aloe Vera, Mentha Piperita (Peppermint) Oil, Mentha Viridis (Spearmint) Leaf Oil, Menthol, Sodium Benzoate, Stevia Rebaudiana Leaf/Stem Extract

How you'd like it
Size Single (120g)
  • Free shipping — over $25
  • Natural — only clean ingredients
  • Cancel anytime — no skip fees
  • 30 day trial — easy returns
Full ingredients ↓ Clinical whitepaper (PDF) Shipping & returns

What's inside

Clean, listed.

Sixteen ingredients. Each one chosen for a reason — nothing hiding behind "natural flavors."

Seen up close

Specimen plates

FIG. 01
Water
Water Purified
FIG. 02
Xylitol
Xylitol Birch-derived
FIG. 03
Aloe Vera
Aloe Vera Leaf Extract
FIG. 04
Mentha Viridis
Mentha Viridis Spearmint

Purified

The base of every honest formula — nothing hidden, nothing fancy.

Plant-derived

Helps maintain moisture and contributes to a smooth, even paste texture.

Vegetable-derived

A humectant that helps the paste stay smooth and keeps your mouth feeling hydrated after brushing.

Food-grade

Helps keep the formula fresh without parabens or harsh synthetic preservatives.

10% active

The same mineral as your enamel — in nano and micro particle sizes to support remineralization and help reduce sensitivity over time.

Plant-derived

Starves cavity-causing bacteria of their fuel source without disrupting the rest of your oral microbiome.

Amino acid-derived

A gentle, sulfate-free surfactant that cleans without stripping enamel or gums.

Particle science

Two mineral sizes. Two repair jobs.

Nano- and micro-hydroxyapatite are the same enamel-like mineral at two different scales. One is small enough to slip into the cracks. One stays on the surface and seals it. We put both in the tube — at 10% concentration — because the job has two layers.

Nano
20–100 nm
Deep repair
Micro
5–10 microns
Surface seal
Nano-hydroxyapatite

The deep-repair crystal.

Ultra-fine, rod-shaped crystals are small enough to mimic the mineral structure of natural enamel — and small enough to reach into microscopic defects you can't see.

Scale
About 20–100 nanometers. Shown here as a single elongated hexagonal prism, much larger than life.
Shape
Needle-like, with six flat sides — the hexagonal crystal system hydroxyapatite forms naturally.
Role
Slips past the outer surface, fills tiny cracks, and helps block the exposed pathways linked to sensitivity.
Drag · to rotate
Scroll · to explore
Single hexagonal crystal CylinderGeometry · 6 radial segments
Drag · to rotate
Scroll · to explore
Fused crystallite aggregate InstancedMesh · 380 hexagonal rods
Micro-hydroxyapatite

The surface-seal cluster.

Larger mineral clusters stay on the enamel surface, where they fill visible texture, smooth the bite, and buffer the everyday acid exposure that wears teeth down.

Scale
Typically 5–10 microns — fifty to five hundred times larger than an individual nano crystal.
Shape
Not one giant rod, but hundreds of tiny crystallites fused into a porous, mostly spherical cluster.
Role
Builds a surface shield that fills visible texture, polishes the enamel feel, and buffers acid exposure from food and drink.
Anatomy of the tube

Six things worth pointing at .

"We didn't formulate this paste from a marketing brief. We formulated it from a literature review." — R&D, Klyyr
01 The mineral
10% Hydroxyapatite
Nano- + micro-HAp at the upper concentration backed by Japanese clinical data.
02 Acid-neutral
pH 7.4
Same as saliva. The enamel stays in the room.
03 By design
Fluoride · 0 ppm
Hydroxyapatite is the alternative — not the supplement to fluoride.
One+
04 No detergent
SLS-free
Sodium cocoyl glutamate, coconut-derived. Foams gently, doesn't strip.
05 Recyclable
Aluminum tube
Wash, flatten, drop in the curbside bin. Lid is a separate stream.
06 Nothing extra
16 ingredients
Each one is doing work. None of them are there to look good on a label.
Form
Paste
Net wt.
120 g · 4.23 oz
Brushings
~ 90
pH
7.4 ± 0.2
Abrasivity (RDA)
62 · low
Country
USA based
A happy couple walking through a colorful meadow
What you'll feel

The first thirty days.

Hydroxyapatite is biomimetic — your body recognizes it, so it gets to work fast. Here's the realistic timeline.

  1. DAY 01
    Cleaner mouth, no burn.
    First brush — the slip feels mineral, not detergent. Breath is fresh, gums calm. The absence of foam is the whole point.
    sensory
  2. DAY 07
    Sensitivity quiets down.
    Nano-HAp has had a week to occupy the dental tubules. Cold water, sweet, sour — the wince retreats.
    tubules
  3. DAY 14
    Surface starts to gleam.
    Micro-HAp builds a thin, glassy layer over enamel. 96% of clinical participants reported visibly reduced sensitivity by now.
    enamel
  4. DAY 30
    Routine, not regimen.
    What was a switch is now a habit. Tubes last about a month. The next one is already on the way if you subscribed.
    habit
96%
reported less sensitivity in 14 days
92%
showed measurable remineralization
n = 212
double-blind, independent lab
How it stacks

Compared, without spin .

Fluoride works. We just think hydroxyapatite — at this strength — works better, and asks less of you in return.

Spec
Honest table.
Hydroxyapatite, 10%
Klyyr ONE+
Conventional
Fluoride paste
2-5% Hydroxyapatite
Other HAp brands
Active ingredient
10% nano + micro HAp
Sodium Fluoride
2-5% HAp (nano or micro)
Remineralizes enamel
✓
partial
partial
Fills dental tubules
✓
—
✓
Acid-neutral pH 7.4
✓
acidic
varies
Safe if swallowed
✓
warn for children
✓
Reef + biome safe
✓
—
varies
SLS-free
✓
—
varies
Made in USA
✓
varies
varies
Price / month
$9.71
$6.99
$15.95
Hydroxyapatite, 10%
Klyyr ONE+
Active ingredient
10% nano + micro HAp
Remineralizes enamel
✓
Fills dental tubules
✓
Acid-neutral pH 7.4
✓
Safe if swallowed
✓
Reef + biome safe
✓
SLS-free
✓
Made in USA
✓
Price / month
$9.71
Conventional
Fluoride paste
Active ingredient
Sodium Fluoride
Remineralizes enamel
partial
Fills dental tubules
—
Acid-neutral pH 7.4
acidic
Safe if swallowed
warn for children
Reef + biome safe
—
SLS-free
—
Made in USA
varies
Price / month
$6.99
2-5% Hydroxyapatite
Other HAp brands
Active ingredient
2-5% HAp (nano or micro)
Remineralizes enamel
partial
Fills dental tubules
✓
Acid-neutral pH 7.4
varies
Safe if swallowed
✓
Reef + biome safe
varies
SLS-free
varies
Made in USA
varies
Price / month
$15.95

Categories generalized. Specific competitor formulas vary — full citations in our whitepaper.

From people who use it

2,418 reviews,
4.86 average.

We don't pay for reviews. We don't gate them. We don't filter for stars. Every quote is from a verified subscriber.

★ ★ ★ ★ ★ 87%
★ ★ ★ ★ ★ 9%
★ ★ ★ ★ ★ 2%
★ ★ ★ ★ ★ 1%
★ ★ ★ ★ ★ 1%
Mint forward 248 Reduces sensitivity 412 Foam-light 203 Family approved 351
★ ★ ★ ★ ★
"I read 14 ingredient labels. Bought this one."

I have been chasing a fluoride-free paste that isn't either gritty or actually a gel. Klyyr is the first one that brushes like real toothpaste. The mineral aftertaste is mild and gone in a minute. My dentist asked what I switched to at my last cleaning.

Mira K.
Verified · 6 mo subscriber · Brooklyn, NY
★ ★ ★ ★ ★
"Cold drinks again. That's the headline."

Sensitivity was a problem I had given up trying to solve. I noticed a difference around the two-week mark — not zero, but real. Now I can drink iced coffee without choosing the side of my mouth first.

Daniel R.
Verified · 4 mo subscriber · Austin, TX
★ ★ ★ ★ ★
"Love the formula. The cap deserves a redesign."

Tube is gorgeous, formula is great, kids tolerate the mint without complaining. The flip cap is a little stiff out of the box. Took it down a star — but I'm not going back.

Priya S.
Verified · 3 mo subscriber · Seattle, WA
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