Fully listed ingredients.
Sixteen ingredients, each named and explained. No SLS, no artificial dyes, and nothing hidden behind a catch-all flavor label.
- 16 ingredients
- Fully listed
Introducing ONE+
Brush with what teeth are made of.
10% nano and micro hydroxyapatite — the mineral your enamel is already made of. Both particle sizes are in the tube, at a combined 10%.
- Ingredients
- 16
- nHAp + mHAp
- 10%
- No decay-index
- 89%
Loading 3D model
NEW
10% HAp
new fluoride-free toothpaste
Best overall 2026 · Exact-Net →
One+
fluoride-free, natural, hydroxyapatite toothpaste
- Made with the mineral teeth are made of
- RDA 62
- 10% nano + micro hydroxyapatite
- No SLS · no artificial dyes · fluoride-free
60-day guarantee
Tested every lot
Ships in 1-2 days
Full ingredient list — 16
Water, Sorbitol, Glycerin, Potassium Sorbate, Hydroxyapatite (nano & micro), Xylitol, Sodium Cocoyl Glutamate, Cellulose Gum, Xanthan Gum, Zinc Citrate, Aloe Vera, Mentha Piperita (Peppermint) Oil, Mentha Viridis (Spearmint) Leaf Oil, Menthol, Sodium Benzoate, Stevia Rebaudiana Leaf/Stem Extract.
How to use
Use a pea-sized amount on a soft-bristle brush for two minutes, morning and night. Spit — don't rinse — so a light mineral film stays on the teeth. For children under 3 use a rice-grain amount; ages 3–6 use a pea-sized amount with supervision.
Product facts
Paste. 120 g · 4.23 oz per tube, approximately 90 brushings. pH 7.4 ± 0.2. Abrasivity RDA 62 — low. Fluoride 0 ppm. SLS-free, no artificial dyes. Developed and fulfilled in Utah, USA.
Shipping & returns
In-stock orders are processed in 1–2 business days, excluding weekends and holidays. Carrier transit time is additional. Eligible U.S. orders of $20 or more after discounts qualify for free standard shipping. Contact us within 60 days for help under our satisfaction guarantee; see the refund policy for terms.
How the subscription works
Your chosen pack on your selected schedule at the subscriber price. Skip a delivery, push the date back, swap pack size, or cancel from your account. No skip fees and no phone call.
89%
View the study →
of adults using 10% hydroxyapatite had no decay-index increase over 18 months, non-inferior to 1450 ppm fluoride.
03 — What is Klyyr?
Three / Chapters
What is klyyr?
10% on the label.
We built Klyyr for people who read labels: clearly disclosed 10% nano + micro hydroxyapatite in a fully listed 16-ingredient formula.
- 10% nHAp
- Fluoride-free
Twice a day.
Peppermint and spearmint. Two minutes, morning and night.
- Daily use
- Peppermint + spearmint
04 — The science
What the evidence says
In an 18-month adult study, 10% HAp performed as well as fluoride.
What the studies measured.
Published studies help explain why hydroxyapatite is used in oral care. The research below evaluated other toothpaste formulations or laboratory models—not Klyyr One+. We cite the exact result, study type, and limitations so ingredient-level evidence is not mistaken for a Klyyr clinical claim.
05 — Journal
VIEW ALL →The slow read .
Notes on the formula, the studies, and the two of us. Monthly, when there's something worth saying.
02
03
04
Small Crystals, Big Repairs: What Makes Hydroxyapatite Bioavailable to Your Enamel
Stream or String? What Clinical Trials Reveal About Water Flossers and Traditional Floss
Small Teeth, Big Job: How Baby Teeth Shape Your Child's Smile for Life
+ 57 more
See all journal entries
06 — Hydroxyapatite
Interactive particle visualization of a tooth formed from hydroxyapatite mineral particles.
The mineral
The mineral, explained.
Hydroxyapatite is a calcium phosphate mineral closely related to enamel and dentin. Published studies have examined it in toothpastes for remineralization, sensitivity, stain removal, and caries—results depend on the formula. One+ uses 10% nano and micro hydroxyapatite, with both particle sizes and every other ingredient listed.
Biocompatible
Fluoride alternative
Clinically studied
Nano + micro
01 How does hydroxyapatite compare with fluoride?
Hydroxyapatite is a fluoride-free alternative with growing clinical evidence. In one 18-month adult study, a 10% HAp toothpaste was non-inferior to 1450 ppm fluoride for the study's primary caries endpoint. That study tested a different formula, so it is ingredient-level evidence—not a Klyyr clinical result. Read the hydroxyapatite vs fluoride comparison.
02 Why nano and micro hydroxyapatite?
Nano and micro refer to particle-size ranges. Published ingredient research examines how smaller particles interact with microscopic defects and dentinal tubules, while larger particles remain closer to the tooth surface. One+ includes both at a combined 10% concentration. Read nano vs micro hydroxyapatite toothpaste.
03 Can children use it?
For children under 3, use a rice-grain amount; for ages 3–6, use a pea-sized amount. A caregiver should supervise brushing and encourage children to spit rather than intentionally swallow. Ask your child's dentist about individual needs, especially when switching from fluoride. See hydroxyapatite toothpaste for kids.
04 Can I use it during pregnancy?
All 16 ingredients are disclosed so you can review them with your dentist or OB. Pregnancy can change oral-health needs, so ask your care team before making a material change to your routine.
05 What's the actual ingredient list?
Water, Sorbitol, Glycerin, Potassium Sorbate, Hydroxyapatite (nano & micro), Xylitol, Sodium Cocoyl Glutamate, Cellulose Gum, Xanthan Gum, Zinc Citrate, Aloe Vera, Mentha Piperita (Peppermint) Oil, Mentha Viridis (Spearmint) Leaf Oil, Menthol, Sodium Benzoate, Stevia Rebaudiana Leaf/Stem Extract. Paste any toothpaste list into the toothpaste ingredient checker.
06 How does the subscription work?
Choose an available delivery schedule and the current selling-plan savings will be shown before checkout. Skip, pause, or cancel from your account. Shipping cost and eligibility are confirmed at checkout.
07 Is the tube recyclable?
The tube body is aluminum and the cap is HDPE. Rinse and separate the components, then recycle each one where accepted locally.
08 Why does it cost more than some drugstore toothpastes?
One+ contains a clearly disclosed 10% nano + micro hydroxyapatite blend, comes in a 120 g aluminum tube, and lists all 16 ingredients. Current one-time and subscription prices are shown before checkout.
09 — Independent research
Ask someone who isn't us.
Send this to ChatGPT and read what it finds. Change the question if ours is the wrong one.