Switching

Risk-based · Ask your dentist first

When you stop using fluoride.

Quick answer

Nothing dramatic happens the day you stop. Fluoride toothpaste works mainly at the tooth surface, helping slow mineral loss and repair early lesions. When you stop, that topical effect fades with the last brushing. Whether it matters depends on your cavity risk: diet, saliva, plaque control, dental history, and what you brush with instead.

Hydroxyapatite toothpaste is the main fluoride-free option with clinical caries data. In one 18-month adult study, a 10% HAp toothpaste was non-inferior to 1450 ppm fluoride for the primary caries endpoint. The study tested a different formula, and it does not settle the question for every mouth. If you get cavities easily, talk to your dentist before you switch.

  • 01

    Nothing happens overnight

    Teeth don't change the day you stop. Cavities develop over months, driven mostly by diet and plaque.

  • 02

    Risk decides

    Low-risk adults and high-risk mouths are different cases. Your dentist knows which you are.

  • 03

    Replace it, don't just drop it

    If you stop fluoride, brush with something that has clinical caries data. HAp is the main fluoride-free option.

Topic Fluoride stopped What changes Klyyr One+ If you switch to HAp
Topical fluoride Fades after your last fluoride brushing None. One+ is 0 ppm
Cavity protection Depends on your risk and your replacement One 18-month adult trial of another 10% HAp paste: non-inferior on its endpoint
Early enamel lesions Fluoride's best-known job HAp studied for early lesions in other formulas
Higher-risk mouths Dry mouth, braces, exposed roots, frequent cavities Ask your dentist before switching
Water fluoridation Utah (May 2025) and Florida (July 2025) ended it statewide Ask whether that changes your plan
Children Ask the child's dentist before stopping Rice-grain under 3, pea-sized 3 to 6. Spit
Dental checkups Your dentist can spot early changes Keep them

This page is general information, not a treatment plan. The HAp caries trial tested a different formula. Water fluoridation status comes from Utah and Florida state law. One+ facts come from its current label.

Sources behind this answer

These sources describe how fluoride works, what the HAp caries trial measured, and the water policy changes behind many of these searches. None tested One+.

  1. American Dental Association

    Fluoride: topical and systemic

    The ADA describes how fluoride protects teeth at the surface and supports fluoride toothpaste for cavity prevention, with professional fluoride for people at higher risk.

    Read the ADA fluoride overview

  2. 18-month adult clinical trial · different formula

    Caries endpoint

    In one 18-month adult study, a 10% HAp toothpaste was non-inferior to 1450 ppm fluoride for the primary caries endpoint. The study tested a different formula.

    Read the 18-month non-inferiority study

  3. KUER · Utah public radio · March 2025

    Utah ends water fluoridation

    Utah became the first state to ban fluoride in public drinking water, effective May 7, 2025. Florida's statewide ban followed on July 1, 2025.

    Read the KUER report

  4. American Dental Association

    Toothpaste overview

    The ADA describes what toothpaste ingredients do, recommends fluoride toothpaste, gives the rice-grain and pea-sized amounts for children, and lists the ingredients most often reported as irritants.

    Read the ADA toothpaste overview

How to choose

Talk to your dentist first if

You get cavities often, have dry mouth, wear braces, have exposed roots, or are choosing for a child. Do not stop a fluoride routine your dentist prescribed.

A HAp paste may fit if

You and your dentist agree a fluoride-free routine suits your risk, and you want a disclosed dose. One+ lists 10% nano + micro hydroxyapatite.

See a dentist if you notice

New sensitivity, chalky white spots, brown or dark spots, or pain. Those are reasons for an exam, not a toothpaste change.

The Klyyr One+ formula

One+ is fluoride-free toothpaste with a clearly disclosed 10% nano + micro hydroxyapatite blend, 16 listed ingredients, peppermint + spearmint, no SLS, and no artificial dyes.

  • 01

    10% hydroxyapatite

    Combined nano + micro hydroxyapatite, disclosed on the label. Ten percent is not a universal efficacy threshold.

  • 02

    16 listed ingredients

    Water, Sorbitol, Glycerin, Potassium Sorbate, Hydroxyapatite (nano & micro), Xylitol, Sodium Cocoyl Glutamate, Cellulose Gum, Xanthan Gum, Zinc Citrate, Aloe Vera, Mentha Piperita (Peppermint) Oil, Mentha Viridis (Spearmint) Leaf Oil, Menthol, Sodium Benzoate, Stevia Rebaudiana Leaf/Stem Extract.

  • 03

    What is not in it

    0 ppm fluoride. No SLS. No artificial dyes. Sodium cocoyl glutamate is the surfactant.

  • 04

    120 g aluminum tube

    4.23 oz, approximately 90 brushings. Aluminum tube, HDPE cap. Recycle where accepted locally.

In short

Stopping fluoride toothpaste removes a topical protection. It is a reasonable choice for some adults and a poor one for high-risk mouths. Replace it with something that has evidence, and keep your dentist in the loop.

01 Will my teeth get worse if I stop using fluoride toothpaste?

Not overnight. Your risk depends on diet, saliva, plaque, and what you brush with instead. High-risk mouths lose more protection than low-risk ones. Ask your dentist which you are.

02 Is it safe to stop using fluoride toothpaste?

For some low-risk adults, a fluoride-free routine can be reasonable with a dentist's agreement. People with frequent cavities, dry mouth, braces, or exposed roots should ask before stopping.

03 What can I use instead of fluoride toothpaste?

Hydroxyapatite toothpaste is the main fluoride-free option with clinical caries data. One 18-month adult trial of a 10% HAp paste was non-inferior to 1450 ppm fluoride on its primary endpoint. See hydroxyapatite vs fluoride.

04 My state stopped fluoridating water. Should I change toothpaste?

Utah and Florida ended statewide water fluoridation in 2025. Ask your dentist whether that changes your routine, especially for children. It may be a reason to keep fluoride toothpaste rather than drop it.

05 Should children stop using fluoride toothpaste?

Ask the child's dentist. If you use One+, use a rice-grain amount under 3 and a pea-sized amount from 3 to 6, supervise brushing, and encourage spitting. See HAp toothpaste for kids.

Read the full FAQ →

Shop

One tube. Pick the question you came with.

One+ is the only product in each collection. Pick the page that matches what you came for.

  1. 01 Switching to hydroxyapatiteOne tube to start with.
  2. 02 Fluoride-free toothpaste0 ppm fluoride, disclosed 10% HAp.
  3. 03 10% hydroxyapatite toothpasteThe percentage is on the tube.
ONE+
If you go fluoride-free, go with a disclosed 10% hydroxyapatite.
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