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This is every toothpaste Klyyr sells. Today that is one formula, One+: a fluoride-free toothpaste with 10% nano + micro hydroxyapatite, sodium cocoyl glutamate instead of SLS, no artificial dyes, and 16 listed ingredients in a 120 g tube.
Choosing a toothpaste starts with the label. The 2026 Toothpaste Transparency Report compares 50 labels, and the toothpaste ingredient checker flags fluoride, SLS, and dyes in any list you paste. If you are deciding whether to leave fluoride, start with fluoride-free toothpaste, which compares 35 labels and says who should keep fluoride.
10% Hydroxyapatite
Nano + micro hydroxyapatite at a clearly disclosed combined concentration.
Fluoride-free
A fluoride-free formula by design.
Twice a day
Brush, spit, leave it.
Utah, USA
Developed and fulfilled in Utah, USA.
One formula. Clearly disclosed 10% HAp. All 16 ingredients listed.
Shop the collection
One+ toothpaste
One+
Hydroxyapatite toothpaste.
Fluoride-free toothpaste with a clearly disclosed 10% nano + micro hydroxyapatite blend and a fully listed 16-ingredient formula.
View ingredients
Water, Sorbitol, Glycerin, Potassium Sorbate, Hydroxyapatite (nano & micro), Xylitol, Sodium Cocoyl Glutamate, Cellulose Gum, Xanthan Gum, Zinc Citrate, Aloe Vera, Mentha Piperita (Peppermint) Oil, Mentha Viridis (Spearmint) Leaf Oil, Menthol, Sodium Benzoate, Stevia Rebaudiana Leaf/Stem Extract
Interactive particle visualization of a tooth formed from hydroxyapatite mineral particles.
The mineral
The mineral, explained.
Hydroxyapatite is a calcium phosphate mineral closely related to enamel and dentin. Published studies have examined it in toothpastes for remineralization, sensitivity, stain removal, and caries—results depend on the formula. One+ uses 10% nano and micro hydroxyapatite, with both particle sizes and every other ingredient listed.
01 How does hydroxyapatite compare with fluoride?
Hydroxyapatite is a fluoride-free alternative with growing clinical evidence. In one 18-month adult study, a 10% HAp toothpaste was non-inferior to 1450 ppm fluoride for the study's primary caries endpoint. That study tested a different formula, so it is ingredient-level evidence—not a Klyyr clinical result. Read the hydroxyapatite vs fluoride comparison.
02 Why nano and micro hydroxyapatite?
Nano and micro refer to particle-size ranges. Published ingredient research examines how smaller particles interact with microscopic defects and dentinal tubules, while larger particles remain closer to the tooth surface. One+ includes both at a combined 10% concentration. Read nano vs micro hydroxyapatite toothpaste.
03 Can children use it?
For children under 3, use a rice-grain amount; for ages 3–6, use a pea-sized amount. A caregiver should supervise brushing and encourage children to spit rather than intentionally swallow. Ask your child's dentist about individual needs, especially when switching from fluoride. See hydroxyapatite toothpaste for kids.
04 What's the actual ingredient list?
Water, Sorbitol, Glycerin, Potassium Sorbate, Hydroxyapatite (nano & micro), Xylitol, Sodium Cocoyl Glutamate, Cellulose Gum, Xanthan Gum, Zinc Citrate, Aloe Vera, Mentha Piperita (Peppermint) Oil, Mentha Viridis (Spearmint) Leaf Oil, Menthol, Sodium Benzoate, Stevia Rebaudiana Leaf/Stem Extract. Paste any toothpaste list into the toothpaste ingredient checker.