Compare

Public labels ยท 27 September 2026 ยท No head-to-head trial

Klyyr vs. Twice.

Quick answer

Klyyr vs Twice compares two fluoride-free pastes that both publish their hydroxyapatite dose. Twice Happy Mint uses 5% nano-hydroxyapatite and pairs it with papain and bromelain enzymes for surface-stain brightening, in a 23-ingredient formula. Klyyr One+ uses 10% nano + micro hydroxyapatite in 16 ingredients.

Both are SLS-free and peroxide-free. Twice adds hydrated silica, two surfactants, arginine, and green tea; One+ lists no silica and uses one surfactant. Twice is 3.4 oz and One+ is 4.23 oz.

Couple walking through a meadow
Klyyr One+ toothpaste in a clean flat lay

5% with enzymes or 10% with two particle sizes

  • 01

    Both publish a number

    Twice states 5% nano-HAp. One+ states 10% nano + micro. A higher percentage alone is not a clinical ranking.

  • 02

    Twice adds enzymes

    Papain and bromelain are there to loosen the protein film that holds surface stains. One+ makes no enzyme-whitening claim.

  • 03

    Formula length differs

    Twice lists 23 ingredients; One+ lists 16.

Topic Official product information Twice Klyyr One+ One+
Hydroxyapatite 5% nano-HAp 10% nano + micro, combined
Fluoride None 0 ppm
Peroxide None None
SLS None None
Surfactants Cocamidopropyl betaine and sodium cocoyl glutamate Sodium cocoyl glutamate
Silica Hydrated silica listed None listed
Brightening approach Papain and bromelain enzymes No enzyme or bleaching claim
Flavor Peppermint, spearmint, cardamom Peppermint + spearmint
Net contents 3.4 oz 4.23 oz / 120 g

Twice details come from the official Happy Mint product page reviewed 27 September 2026. Twice's classic fluoride toothpastes are different formulas with no hydroxyapatite. One+ facts come from the current Klyyr label.

Sources reviewed

This is a public-label comparison. The linked official pages are the source of truth for each brand, and neither product has been tested against the other in a clinical trial cited here.

  1. Official competitor page ยท reviewed 27 September 2026

    Twice facts

    Twice publishes 5% nano-hydroxyapatite in a 23-ingredient, fluoride-free, peroxide-free Happy Mint paste with papain and bromelain enzymes, two surfactants, and a 3.4 oz tube.

    Read the current Twice source

  2. Current Klyyr label

    One+ formula facts

    One+ publishes a combined 10% nano + micro hydroxyapatite blend, 16 ingredients, 0 ppm fluoride, no SLS, RDA 62, and a 120 g tube.

    Read the current One+ product page

  3. 50-product label audit ยท August 2026

    Same rules for every brand

    The Klyyr transparency report records a percentage only when a brand or official label states it. Undisclosed values are never filled with retailer guesses.

    Read the audit method and source table

Which one fits your routine?

Twice may fit if

You want a nano-HAp paste with enzyme brightening, a cardamom-mint flavor, or a brand with a dentist advisor.

One+ may fit if

You want a 10% dose with nano and micro particles, no silica, and a shorter 16-ingredient label.

Check the exact tube

Twice sells fluoride and fluoride-free pastes, and its classic fluoride formulas contain no hydroxyapatite.

The Klyyr One+ formula

One+ is a fluoride-free daily paste with a disclosed 10% nano + micro hydroxyapatite blend, 16 listed ingredients, peppermint + spearmint, no SLS, and no artificial dyes.

  • 01

    10% nano + micro

    One combined 10% hydroxyapatite concentration with both particle-size ranges named on the label.

  • 02

    16 listed ingredients

    Water, Sorbitol, Glycerin, Potassium Sorbate, Hydroxyapatite (nano & micro), Xylitol, Sodium Cocoyl Glutamate, Cellulose Gum, Xanthan Gum, Zinc Citrate, Aloe Vera, Peppermint Oil, Spearmint Leaf Oil, Menthol, Sodium Benzoate, and Stevia.

  • 03

    0 ppm fluoride ยท no SLS

    One+ is fluoride-free, peroxide-free, and made without SLS, titanium dioxide, or artificial dyes.

  • 04

    120 g aluminum tube

    4.23 oz with an HDPE cap. Recycle each component where accepted locally.

In short

Twice pairs 5% nano-HAp with enzymes. One+ doubles the published dose and adds micro particles. Both tell you the number.

01 How much hydroxyapatite is in Twice toothpaste?

Twice Happy Mint lists 5% nano-hydroxyapatite. One+ lists 10% combined nano + micro.

02 Is Twice toothpaste fluoride-free?

Happy Mint is fluoride-free. Twice also sells fluoride toothpastes, so check the carton.

03 Is 10% better than 5% hydroxyapatite?

Many published trials used 10%, but they tested other formulas. A higher number on its own does not prove a better result.

04 What do papain and bromelain do?

They are protein-breaking enzymes from papaya and pineapple. Twice uses them to loosen the protein film that holds surface stains. One+ does not contain them.

05 Are both SLS-free?

Yes. Twice uses cocamidopropyl betaine and sodium cocoyl glutamate. One+ uses sodium cocoyl glutamate.

Read the complete FAQ โ†’

ONE+
10% nano + micro, in 16 ingredients.
Shop One+ โ€” $12.95 Subscribe & save 25%